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A charged residue in S4 regulates coupling among the activation gate, voltage, and Ca2+ sensors in BK channels., Zhang G, Yang H, Liang H, Yang J, Shi J, McFarland K, Chen Y, Cui J., J Neurosci. September 10, 2014; 34 (37): 12280-8.
Anion permeation in calcium-activated chloride channels formed by TMEM16A from Xenopus tropicalis., Reyes JP, López-Rodríguez A, Espino-Saldaña AE, Huanosta-Gutiérrez A, Miledi R, Martínez-Torres A., Pflugers Arch. September 1, 2014; 466 (9): 1769-77.
Analysis of the pharmacological properties of chicken melanocortin-2 receptor (cMC2R) and chicken melanocortin-2 accessory protein 1 (cMRAP1)., Barlock TK, Gehr DT, Dores RM., Gen Comp Endocrinol. September 1, 2014; 205 260-7.
A device for emulating cuff recordings of action potentials propagating along peripheral nerves., Rieger R, Schuettler M, Chuang SC., IEEE Trans Neural Syst Rehabil Eng. September 1, 2014; 22 (5): 937-45.
A single codon insertion in PICALM is associated with development of familial subvalvular aortic stenosis in Newfoundland dogs., Stern JA, White SN, Lehmkuhl LB, Reina-Doreste Y, Ferguson JL, Nascone-Yoder NM, Meurs KM., Hum Genet. September 1, 2014; 133 (9): 1139-48.
A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia., Tsoi H, Yu AC, Chen ZS, Ng NK, Chan AY, Yuen LY, Abrigo JM, Tsang SY, Tsui SK, Tong TM, Lo IF, Lam ST, Mok VC, Wong LK, Ngo JC, Lau KF, Chan TF, Chan HY., J Med Genet. September 1, 2014; .
A Novel Long-Acting Glucagon-Like Peptide-1 Agonist with Improved Efficacy in Insulin Secretion and β-Cell Growth., Kim HY, Hwang JI, Moon MJ, Seong JY., Endocrinol Metab (Seoul). September 1, 2014; 29 (3): 320-7.
Andrés Carrasco (1946-2014)., Blumberg B., Dev Biol. September 1, 2014; 393 (1): 1-2.
A single crossing-over event in voltage-sensitive Na+ channel genes may cause critical failure of dengue mosquito control by insecticides., Hirata K, Komagata O, Itokawa K, Yamamoto A, Tomita T, Kasai S., PLoS Negl Trop Dis. August 28, 2014; 8 (8): e3085.
APTE: identification of indirect read-out A-DNA promoter elements in genomes., Whitley DC, Runfola V, Cary P, Nazlamova L, Guille M, Scarlett G., BMC Bioinformatics. August 26, 2014; 15 288.
A highly effective TALEN-mediated approach for targeted gene disruption in Xenopus tropicalis and zebrafish., Liu Y, Luo D, Lei Y, Hu W, Zhao H, Cheng CH., Methods. August 15, 2014; 69 (1): 58-66.
An allosteric model of the inositol trisphosphate receptor with nonequilibrium binding., Jia C, Jiang D, Qian M., Phys Biol. August 14, 2014; 11 (5): 056001.
A tethered delivery mechanism explains the catalytic action of a microtubule polymerase., Ayaz P, Munyoki S, Geyer EA, Piedra FA, Vu ES, Bromberg R, Otwinowski Z, Grishin NV, Brautigam CA, Rice LM., Elife. August 5, 2014; 3 e03069.
A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels., Rinné S, Renigunta V, Schlichthörl G, Zuzarte M, Bittner S, Meuth SG, Decher N, Daut J, Preisig-Müller R., Pflugers Arch. August 1, 2014; 466 (8): 1559-70.
A critical role of non-classical MHC in tumor immune evasion in the amphibian Xenopus model., Haynes-Gilmore N, Banach M, Edholm ES, Lord E, Robert J., Carcinogenesis. August 1, 2014; 35 (8): 1807-13.
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics., Lundby A, Rossin EJ, Steffensen AB, Acha MR, Newton-Cheh C, Pfeufer A, Lynch SN, QT Interval International GWAS Consortium (QT-IGC), Olesen SP, Brunak S, Ellinor PT, Jukema JW, Trompet S, Ford I, Macfarlane PW, Krijthe BP, Hofman A, Uitterlinden AG, Stricker BH, Nathoe HM, Spiering W, Daly MJ, Asselbergs FW, van der Harst P, Milan DJ, de Bakker PI, Lage K, Olsen JV., Nat Methods. August 1, 2014; 11 (8): 868-74.
Analogues of etomidate: modifications around etomidate's chiral carbon and the impact on in vitro and in vivo pharmacology., Pejo E, Santer P, Jeffrey S, Gallin H, Husain SS, Raines DE., Anesthesiology. August 1, 2014; 121 (2): 290-301.
Altered inhibition of Cx26 hemichannels by pH and Zn2+ in the A40V mutation associated with keratitis-ichthyosis-deafness syndrome., Sanchez HA, Bienkowski R, Slavi N, Srinivas M, Verselis VK., J Biol Chem. August 1, 2014; 289 (31): 21519-32.
A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel., Aryal P, Abd-Wahab F, Bucci G, Sansom MS, Tucker SJ., Nat Commun. July 8, 2014; 5 4377.
An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter., Fraser R, Chen Y, Guptaroy B, Luderman KD, Stokes SL, Beg A, DeFelice LJ, Gnegy ME., Mol Pharmacol. July 1, 2014; 86 (1): 76-85.
African clawed toads (Xenopus laevis) sense the distance of lateral line stimuli., Dean J, Claas B., J Comp Physiol A Neuroethol Sens Neural Behav Physiol. July 1, 2014; 200 (7): 657-67.
A tri-component conservation strategy reveals highly confident microRNA-mRNA interactions and evolution of microRNA regulatory networks., Lin CC, Mitra R, Zhao Z., PLoS One. July 1, 2014; 9 (7): e103142.
A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity., Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H., Elife. June 30, 2014; 3
Auxin efflux by PIN-FORMED proteins is activated by two different protein kinases, D6 PROTEIN KINASE and PINOID., Zourelidou M, Absmanner B, Weller B, Barbosa IC, Willige BC, Fastner A, Streit V, Port SA, Colcombet J, de la Fuente van Bentem S, Hirt H, Kuster B, Schulze WX, Hammes UZ, Schwechheimer C., Elife. June 19, 2014; 3
A simple behavioral assay for testing visual function in Xenopus laevis., Viczian AS, Zuber ME., J Vis Exp. June 12, 2014; (88):
Allosteric modulation of alpha4beta2 nicotinic acetylcholine receptors by HEPES., Weltzin MM, Huang Y, Schulte MK., Eur J Pharmacol. June 5, 2014; 732 159-68.
Age-related homeostatic midchannel proteolysis of neuronal L-type voltage-gated Ca²⁺ channels., Michailidis IE, Abele-Henckels K, Zhang WK, Lin B, Yu Y, Geyman LS, Ehlers MD, Pnevmatikakis EA, Yang J., Neuron. June 4, 2014; 82 (5): 1045-57.
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry., Bartoi T, Augustinowski K, Polleichtner G, Gründer S, Ulbrich MH., Proc Natl Acad Sci U S A. June 3, 2014; 111 (22): 8281-6.
Anillin regulates cell-cell junction integrity by organizing junctional accumulation of Rho-GTP and actomyosin., Reyes CC, Jin M, Breznau EB, Espino R, Delgado-Gonzalo R, Goryachev AB, Miller AL., Curr Biol. June 2, 2014; 24 (11): 1263-70.
Avermectins differentially affect ethanol intake and receptor function: implications for developing new therapeutics for alcohol use disorders., Asatryan L, Yardley MM, Khoja S, Trudell JR, Hyunh N, Louie SG, Petasis NA, Alkana RL, Davies DL., Int J Neuropsychopharmacol. June 1, 2014; 17 (6): 907-16.
Active repression by RARγ signaling is required for vertebrate axial elongation., Janesick A, Nguyen TT, Aisaki K, Igarashi K, Kitajima S, Chandraratna RA, Kanno J, Blumberg B., Development. June 1, 2014; 141 (11): 2260-70.
Alcohol selectivity of β3-containing GABAA receptors: evidence for a unique extracellular alcohol/imidazobenzodiazepine Ro15-4513 binding site at the α+β- subunit interface in αβ3δ GABAA receptors., Wallner M, Hanchar HJ, Olsen RW., Neurochem Res. June 1, 2014; 39 (6): 1118-26.
An internally modulated, thermostable, pH-sensitive Cys loop receptor from the hydrothermal vent worm Alvinella pompejana., Juneja P, Horlacher R, Bertrand D, Krause R, Marger F, Welte W., J Biol Chem. May 23, 2014; 289 (21): 15130-40.
Analysis of rare variations reveals roles of amino acid residues in the N-terminal extracellular domain of nicotinic acetylcholine receptor (nAChR) alpha6 subunit in the functional expression of human alpha6*-nAChRs., Dash B, Li MD., Mol Brain. May 2, 2014; 7 35.
Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains., Pless SA, Elstone FD, Niciforovic AP, Galpin JD, Yang R, Kurata HT, Ahern CA., J Gen Physiol. May 1, 2014; 143 (5): 645-56.
An intracellular redox sensor for reactive oxygen species at the M3-M4 linker of GABAA ρ1 receptors., Beltrán González AN, Gasulla J, Calvo DJ., Br J Pharmacol. May 1, 2014; 171 (9): 2291-9.
A new set of highly efficient, tag-cleaving proteases for purifying recombinant proteins., Frey S, Görlich D., J Chromatogr A. April 11, 2014; 1337 95-105.
A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors., Luo S, Zhangsun D, Schroeder CI, Zhu X, Hu Y, Wu Y, Weltzin MM, Eberhard S, Kaas Q, Craik DJ, McIntosh JM, Whiteaker P., FASEB J. April 1, 2014; 28 (4): 1842-53.
A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis., Dubaissi E, Rousseau K, Lea R, Soto X, Nardeosingh S, Schweickert A, Amaya E, Thornton DJ, Papalopulu N., Development. April 1, 2014; 141 (7): 1514-25.
A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles., Walentek P, Bogusch S, Thumberger T, Vick P, Dubaissi E, Beyer T, Blum M, Schweickert A., Development. April 1, 2014; 141 (7): 1526-33.
A signal peptide missense mutation associated with nicotine dependence alters α2*-nicotinic acetylcholine receptor function., Dash B, Lukas RJ, Li MD., Neuropharmacology. April 1, 2014; 79 715-25.
Avoiding the formation of vesicles by patch excision from Xenopus oocytes., Thon S, Benndorf K., J Neurosci Methods. March 30, 2014; 225 29-31.
Action of clathrodin and analogues on voltage-gated sodium channels., Peigneur S, Zula A, Zidar N, Chan-Porter F, Kirby R, Madge D, Ilaš J, Kikelj D, Tytgat J., Mar Drugs. March 28, 2014; 12 (4): 2132-43.
A Kir3.4 mutation causes Andersen-Tawil syndrome by an inhibitory effect on Kir2.1., Kokunai Y, Nakata T, Furuta M, Sakata S, Kimura H, Aiba T, Yoshinaga M, Osaki Y, Nakamori M, Itoh H, Sato T, Kubota T, Kadota K, Shindo K, Mochizuki H, Shimizu W, Horie M, Okamura Y, Ohno K, Takahashi MP., Neurology. March 25, 2014; 82 (12): 1058-64.
Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription., Di Cerbo V, Mohn F, Ryan DP, Montellier E, Kacem S, Tropberger P, Kallis E, Holzner M, Hoerner L, Feldmann A, Richter FM, Bannister AJ, Mittler G, Michaelis J, Khochbin S, Feil R, Schuebeler D, Owen-Hughes T, Daujat S, Schneider R., Elife. March 25, 2014; 3 e01632.
Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina., Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M., PLoS One. March 18, 2014; 9 (3): e92113.
A charge-metering method for voltage-mode neural stimulation., Luan S, Constandinou TG., J Neurosci Methods. March 15, 2014; 224 39-47.
A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos., Bhatia S, Monahan J, Ravi V, Gautier P, Murdoch E, Brenner S, van Heyningen V, Venkatesh B, Kleinjan DA., Dev Biol. March 15, 2014; 387 (2): 214-28.
An amyloid inhibitor octapeptide forms amyloid type fibrous aggregates and affects microtubule motility., Biswas A, Kurkute P, Jana B, Laskar A, Ghosh S., Chem Commun (Camb). March 11, 2014; 50 (20): 2604-7.
A linear-encoding model explains the variability of the target morphology in regeneration., Lobo D, Solano M, Bubenik GA, Levin M., J R Soc Interface. March 6, 2014; 11 (92): 20130918.

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